Volume 4 Supplement 2

Selected articles from the Third International Symposium on Optimization and Systems Biology

Proceedings

Edited by Luonan Chen, Xiang-Sun Zhang and Yong Wang

Optimization and Systems Biology. Go to conference site.

Zhangjiajie, China

20 - 22 September 2009

  1. Meeting report

    Optimization meets systems biology

    A report of the 3nd International Symposium on Optimization and Systems Biology, 20-22 September 2009, Zhangjiajie, China.

    Yong Wang, Xiang-Sun Zhang and Luonan Chen

    BMC Systems Biology 2010 4(Suppl 2):S1

    Published on: 13 September 2010

  2. Proceedings

    Computational inference and analysis of genetic regulatory networks via a supervised combinatorial-optimization pattern

    Post-genome era brings about diverse categories of omics data. Inference and analysis of genetic regulatory networks act prominently in extracting inherent mechanisms, discovering and interpreting the related ...

    Binhua Tang, Xuechen Wu, Ge Tan, Su-Shing Chen, Qing Jing and Bairong Shen

    BMC Systems Biology 2010 4(Suppl 2):S3

    Published on: 13 September 2010

  3. Proceedings

    A systems biology approach to identify effective cocktail drugs

    Complex diseases, such as Type 2 Diabetes, are generally caused by multiple factors, which hamper effective drug discovery. To combat these diseases, combination regimens or combination drugs provide an altern...

    Zikai Wu, Xing-Ming Zhao and Luonan Chen

    BMC Systems Biology 2010 4(Suppl 2):S7

    Published on: 13 September 2010

  4. Proceedings

    Inhibition of the interactions between eosinophil cationic protein and airway epithelial cells by traditional Chinese herbs

    The eosinophil cationic protein (ECP) is cytotoxic to bacteria, viruses, parasites and mammalian cells. Cells are damaged via processes of pore formation, permeability alteration and membrane leaking. Some clinic...

    Hao-Teng Chang, Louis J Tseng, Ta-Jen Hung, Blacky T Kao, Wei-Yong Lin, Tan-chi Fan, Margaret Dah-Tsyr Chang and Tun-Wen Pai

    BMC Systems Biology 2010 4(Suppl 2):S8

    Published on: 13 September 2010

  5. Proceedings

    Parameter optimization by using differential elimination: a general approach for introducing constraints into objective functions

    The investigation of network dynamics is a major issue in systems and synthetic biology. One of the essential steps in a dynamics investigation is the parameter estimation in the model that expresses biologica...

    Masahiko Nakatsui, Katsuhisa Horimoto, Masahiro Okamoto, Yasuhito Tokumoto and Jun Miyake

    BMC Systems Biology 2010 4(Suppl 2):S9

    Published on: 13 September 2010

  6. Proceedings

    Comparing biological networks via graph compression

    Comparison of various kinds of biological data is one of the main problems in bioinformatics and systems biology. Data compression methods have been applied to comparison of large sequence data and protein str...

    Morihiro Hayashida and Tatsuya Akutsu

    BMC Systems Biology 2010 4(Suppl 2):S13

    Published on: 13 September 2010