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Volume 5 Supplement 3

The 2010 International Conference on Bioinformatics and Computational Biology (BIOCOMP 2010): Systems Biology

Research

Edited by Ke Zhang, Yunlong Liu, Hamid R Arabnia

BIOCOMP 2010 - The 2010 International Conference on Bioinformatics and Computational Biology.

Las Vegas, NV, USA12-15 July 2010

  1. We present a report of the BIOCOMP'10 - The 2010 International Conference on Bioinformatics & Computational Biology and other related work in the area of systems biology.

    Authors: Ke Zhang, Yunlong Liu, Jack Y Yang, Hamid R Arabnia, Andrzej Niemierko, Arif Ghafoor, Weizhong Li and Youping Deng
    Citation: BMC Systems Biology 2011 5(Suppl 3):I1
  2. For RNA-seq data, the aggregated counts of the short reads from the same gene is used to approximate the gene expression level. The count data can be modelled as samples from Poisson distributions with possibl...

    Authors: Zhongxue Chen, Jianzhong Liu, Hon Keung Tony Ng, Saralees Nadarajah, Howard L Kaufman, Jack Y Yang and Youping Deng
    Citation: BMC Systems Biology 2011 5(Suppl 3):S1
  3. A phylogenetic tree, showing ancestral relations among organisms, is commonly represented as a rooted tree with sets of bifurcating branches (dichotomies) for simplicity, although polytomies (multifurcating br...

    Authors: Guan Ning Lin, Chao Zhang and Dong Xu
    Citation: BMC Systems Biology 2011 5(Suppl 3):S2
  4. State Space Model (SSM) is a relatively new approach to inferring gene regulatory networks. It requires less computational time than Dynamic Bayesian Networks (DBN). There are two types of variables in the lin...

    Authors: Xi Wu, Peng Li, Nan Wang, Ping Gong, Edward J Perkins, Youping Deng and Chaoyang Zhang
    Citation: BMC Systems Biology 2011 5(Suppl 3):S3
  5. Many groups, including our own, have proposed the use of DNA methylation profiles as biomarkers for various disease states. While much research has been done identifying DNA methylation signatures in cancer vs...

    Authors: Linglin Xie, Brent Weichel, Joyce Ellen Ohm and Ke Zhang
    Citation: BMC Systems Biology 2011 5(Suppl 3):S4
  6. Molecular level of biological data can be constructed into system level of data as biological networks. Network motifs are defined as over-represented small connected subgraphs in networks and they have been u...

    Authors: Wooyoung Kim, Min Li, Jianxin Wang and Yi Pan
    Citation: BMC Systems Biology 2011 5(Suppl 3):S5
  7. Breast cancer is one of the leading causes of cancer death for women all over the world and mammography is thought of as one of the main tools for early detection of breast cancer. In order to detect the breas...

    Authors: Jun Liu, Jianxun Chen, Xiaoming Liu, Lei Chun, Jinshan Tang and Youping Deng
    Citation: BMC Systems Biology 2011 5(Suppl 3):S6
  8. To understand transcriptional regulatory networks (TRNs), especially the coordinated dynamic regulation between transcription factors (TFs) and their corresponding target genes during development, computationa...

    Authors: Jigang Wang, Xiaojie Qiu, Yuhua Li, Youping Deng and Tieliu Shi
    Citation: BMC Systems Biology 2011 5(Suppl 3):S8
  9. The availability of temporal measurements on biological experiments has significantly promoted research areas in systems biology. To gain insight into the interaction and regulation of biological systems, math...

    Authors: Omid Ghasemi, Merry L Lindsey, Tianyi Yang, Nguyen Nguyen, Yufei Huang and Yu-Fang Jin
    Citation: BMC Systems Biology 2011 5(Suppl 3):S9
  10. Currently, several systems have been proposed to classify viruses and indicate the relationships between different ones, though each system has its limitations because of the complexity of viral origins and th...

    Authors: Feng Xu, Chen Zhao, Yuhua Li, Jiang Li, Youping Deng and Tieliu Shi
    Citation: BMC Systems Biology 2011 5(Suppl 3):S11
  11. Numerous genetic and genomic datasets related to complex diseases have been made available during the last decade. It is now a great challenge to assess such heterogeneous datasets to prioritize disease genes ...

    Authors: Peilin Jia, Chung-Feng Kao, Po-Hsiu Kuo and Zhongming Zhao
    Citation: BMC Systems Biology 2011 5(Suppl 3):S12
  12. The primary objectives of this paper are: 1.) to apply Statistical Learning Theory (SLT), specifically Partial Least Squares (PLS) and Kernelized PLS (K-PLS), to the universal "feature-rich/case-poor" (also kn...

    Authors: Walker H Land, Xingye Qiao, Daniel E Margolis, William S Ford, Christopher T Paquette, Joseph F Perez-Rogers, Jeffrey A Borgia, Jack Y Yang and Youping Deng
    Citation: BMC Systems Biology 2011 5(Suppl 3):S13
  13. To understand how infectious agents disseminate throughout a population it is essential to capture the social model in a realistic manner. This paper presents a novel approach to modeling the propagation of th...

    Authors: Gonzalo Martín, Maria-Cristina Marinescu, David E Singh and Jesús Carretero
    Citation: BMC Systems Biology 2011 5(Suppl 3):S14