Table 3 List of reactions and parameter values for the aggregation process

Aggregation1

k₇₁<#MisP><#MisP-1>/2.0

2MisP

AggP

k ₇₁

1.0E-8 mol^-1 s^-1

Aggregation2

k₇₁<#MisP><#AggP>

MisP, AggP

2AggP

k ₇₁

1.0E-8 mol^-1 s^-1

Aggregation3

k₇₂<#MisP_Ub><#MisP_Ub-1>/2.0

2MisP_Ub

AggP

k ₇₂

1.0E-8 mol^-1 s^-1

⋮

⋮

⋮

⋮

⋮

⋮

Aggregation10

k₇₂<#MisP_Ub8><#MisP_Ub8-1>/2.0

2MisP_Ub8

AggP

k ₇₂

1.0E-8 mol^-1 s^-1

Aggregation11

k₇₂<#MisP><#MisP_Ub>

MisP, MisP_Ub

AggP

k ₇₂

1.0E-8 mol^-1 s^-1

⋮

⋮

⋮

⋮

⋮

⋮

Aggregation54

k₇₂<#MisP_Ub7><#MisP_Ub8>

MisP_Ub7, MisP_Ub8

AggP

k ₇₂

1.0E-8 mol^-1 s^-1

SequesteringOfAggregates

k₇₃<#AggP>

AggP

SeqAggP

k ₇₃

1.0E-3 s^-1

ProteasomeInhibition

k₇₄<#AggP>

AggP, Proteasome

AggP_Proteasome

k ₇₄

1.0E-5 s^-1