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Table 3 List of reactions and parameter values for the aggregation process

From: An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline

Reaction Kinetic rate law Reactants Products Parameter name Valuea
Aggregation1 k71<#MisP><#MisP-1>/2.0 2MisP AggP k 71 1.0E-8 mol-1 s-1
Aggregation2 k71<#MisP><#AggP> MisP, AggP 2AggP k 71 1.0E-8 mol-1 s-1
Aggregation3 k72<#MisP_Ub><#MisP_Ub-1>/2.0 2MisP_Ub AggP k 72 1.0E-8 mol-1 s-1
Aggregation10 k72<#MisP_Ub8><#MisP_Ub8-1>/2.0 2MisP_Ub8 AggP k 72 1.0E-8 mol-1 s-1
Aggregation11 k72<#MisP><#MisP_Ub> MisP, MisP_Ub AggP k 72 1.0E-8 mol-1 s-1
Aggregation54 k72<#MisP_Ub7><#MisP_Ub8> MisP_Ub7, MisP_Ub8 AggP k 72 1.0E-8 mol-1 s-1
SequesteringOfAggregates k73<#AggP> AggP SeqAggP k 73 1.0E-3 s-1
ProteasomeInhibition k74<#AggP> AggP, Proteasome AggP_Proteasome k 74 1.0E-5 s-1
  1. amol, number of molecules