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Figure 2 | BMC Systems Biology

Figure 2

From: A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells

Figure 2

LDH release measurement of cytotoxicity of palmitate. Confluent HepG2 cells were treated with saturated (palmitate), monounsaturated (oleate) and polyunsaturated (linoleate) free fatty acid at 0.7 mM in presence or absence of TNF-α (0, 20 and 100 ng/ml) for 24 h. Cytotoxicity was measured as % LDH released. Data presented as average +/- s.d. of n = 9 from three independent experiments. *, significantly greater than control; #, significant TNF-α interaction effect (significantly greater than palmitate culture in absence of TNF-α. For both * and #, p < 0.01.

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BMC Systems Biology

ISSN: 1752-0509

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