Skip to main content

Table 2 Enriched gene sets identified by GSEA analysis

From: A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells

Gene Sets SIZE NES NOM p-val
Electron Transport Chain 43 -1.998 0.000
Fatty acid metabolism 33 -1.824 0.000
Glycolysis 55 -1.765 0.000
Oxidative Phosphorylation 30 -1.890 0.004
ROS 26 -1.741 0.009
PPP pathway 15 -1.644 0.010
Cell death 15 -1.631 0.010
ERK pathway 31 -1.620 0.016
Fatty acids beta-oxidation 7 -1.580 0.020
Fatty acid biosynthesis 5 -1.574 0.021
TCA 15 -1.631 0.023
Fructose 19 -1.599 0.026
ERK1 Erk2 Mapk pathway 29 -1.542 0.034
Glutathione 23 -1.520 0.036
Mitochondria 229 -1.945 0.002
  1. Size: number of genes in the gene set; NES: normalized enrichment score; NOM p-val: nominal P value.