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Table 5 Top ranked genes positively related to TG

From: A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells

Accession #

Regr. Coeff.

Gene Name

W73810

2.23E-02

epithelial membrane protein 3 (EMP3), mRNA.

AA485272

1.95E-02

hexokinase 1 (HK1), transcript variant 5, nuclear gene encoding mitochondrial protein, mRNA.

N45129

1.82E-02

glutamate-cysteine ligase, catalytic subunit

T67006

1.80E-02

glucokinase (hexokinase 4) regulatory protein (GCKR), mRNA.

AA486570

1.79E-02

glutathione S-transferase M4 (GSTM4), transcript variant 3, mRNA.

R66006

1.72E-02

acyl-Coenzyme A dehydrogenase, long chain (ACADL), mRNA.

AA495936

1.58E-02

microsomal glutathione S-transferase 1 (MGST1), transcript variant 1a, mRNA.

H93482

1.50E-02

glutamate-cysteine ligase, catalytic subunit

T73468

1.45E-02

glutathione S-transferase A2 (GSTA2), mRNA.

AA676663

1.34E-02

acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain (ACADS), nuclear gene encoding mitochondrial protein, mRNA.

  1. The regression coefficients of all genes range from -0.027 to 0.023