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Table 6 HCR sets mapped to the subsystems in the network along with the size of each subsystem.

From: Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ 661 and proposing alternative drug targets

HCR mapping to subsystems
Metabolic Subsystem HCR Sets in each Subsystem Number of HCRs
Alanine and Aspartate Metabolism 47,81,99,126 4
Arginine and Proline Metabolism 126 1
Biotin Metabolism 33 1
Citric Acid Cycle 98 1
Cofactor Metabolism 7,24,25,26,30,40,56,77,118,123,129 11
Cysteine Metabolism 38 1
Fatty Acid Metabolism 1,43,57,78,86,90,93,94,95,96,97,103,108,110,114,115,116,128,132 19
Folate Metabolism 9,22,28,31,44 5
Glutamate Metabolism 21,27,29,67,76 5
Glycine Serine Threonine Metabolism 19,24,45,111,124 5
Glycolysis 41,42 2
Glyoxylate Metabolism 104 1
Histidine Metabolism 10,70 2
Lysine Metabolism 2,8 2
Membrane Metabolism 23,29,34,35,36,43,46,61,64,65,66,74,79,97,103,106,107,108,109,110,112,113,116,117,130,131,138 27
Methionine Metabolism 27,28,45,91,92 5
Nucleotide Sugar Metabolism 55,59,63,69,75,83,140 7
Other Amino Acid Metabolism 29,48,82,91,92,125,127 7
Pantothenate and CoA Metabolism 12,67,68,81 4
Pentose Phosphate Pathway 32,121 2
Peptidoglycan Metabolism 43,133,134,136,137,100 6
Phenylalanine Tyrosine Tryptophan Metabolism 10,11,20,85,105 5
Polyprenyl Metabolism 16,60,62,77 4
Porphyrin Metabolism 25,30,40,51,52,53 6
Purine Metabolism 5,17,27,49,58,63,73,140 8
Pyrimidine Metabolism 55,59,83,98 4
Pyruvate Metabolism 82 1
Redox Metabolism 39,50,71,72,76,80,100,102 8
Riboflavin Metabolism 6,7,26,30,56 5
Sugar Metabolism 15,42,74,75,87,89,99,119,120,135 10
Thiamine Metabolism 15 1
Transport 39,48,54,71,82,84,87,88,89,101,102,106,110,124,127,139,141,142,143,144,145,146,147 23
Ubiquinone Metabolism 13,122,125 3
Urea Cycle 27,37 2
Valine Leucine Isoleucine Metabolism 3,4,14,18,84,88,139 7