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Figure 1 | BMC Systems Biology

Figure 1

From: From bit to it: How a complex metabolic network transforms information into living matter

Figure 1

Increased glucose information (bits, lower horizontal axis, filled circles) and reduced sensing error (percent, upper horizontal axis, open symbols) cause an increases in fitness (1-s) as estimated through biomass production in the yeast metabolic network via flux balance analysis. The vertical axis shows the selection coefficient s, the difference to the maximal biomass yield at perfectly accurate information. Results are nearly identical for the other four substrates, and are shown for O2 and NH3 in the inset. The dashed horizontal line demarcates a neutral zone, below which (s < 7.33 × 10-8; see text) growth rate increases are selectively neutral.

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