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Figure 8 | BMC Systems Biology

Figure 8

From: Computational cell model based on autonomous cell movement regulated by cell-cell signalling successfully recapitulates the "inside and outside" pattern of cell sorting

Figure 8

Final configurations of aggregates of randomly mixed cells with different GAP PREFERENCE. The common conditions to both cell types: ACTIVATION THRESHOLD = {0.3 or 0.4}; DRAGGING TIME = {6, 10, or 30}; SINGLE MOVING DISTANCE = 1. The areas of the inner cavities within the aggregates in (a) and (b) were 2.597 and 0.834, respectively (SSPs). The CELL DISTRIBUTION RATIOs of the light cell type in (c), (d) and (e) were 5.274 ± 2.402 (S.D.), 8.132 ± 3.406, and 5.326 ± 1.281, respectively. The PERIMETER RATIOs in (c), (d) and (e) were 0.077 ± 0.059, 0.061 ± 0.056 and 0.077 ± 0.058, respectively.

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