Table 1 Summary of cell arrangement patterns in the in silico aggregates

Fig. 2a-c,e; Fig. 3a,b,e; Fig. 4a,b,g,h; Fig. 5a-c,e,f; Fig. 6a,b

Fig. 4c,d; Fig. 5d; Fig. 6c-e

Fig. 4i; Fig. 6f

Fig. 2d: (0.774 ± 0.683, 3.059 ± 2.188) or (1.868 ± 1.095, 0.590 ± 0.517).

Fig. 2f: (1.056 ± 0.143, 0.092 ± 0.270) or (0.872 ± 0.160, 1.057 ± 0.215).

Fig. 2g: (0.684 ± 0.336, 2.203 ± 1.109) or (1.571 ± 0.616, 0.564 ± 0.302).

Fig. 2h: (0.767 ± 0.320, 2.261 ± 1.564) or (1.710 ± 1.335, 0.585 ± 0.291).

Fig. 2i: (1.364 ± 0.651, 1.295 ± 1.174) or (1.167 ± 0.687, 1.451 ± 0.996).

Fig. 2j: (1.545 ± 0.757, 0.935 ± 0.624) or (0.899 ± 0.524, 1.454 ± 0.763).

Fig. 3c: (0.552 ± 0.202, 1.751 ± 1.168) or (2.122 ± 1.046, 0.732 ± 0.337).

Fig. 3d: (0.778 ± 0.416, 2.055 ± 1.429) or (1.676 ± 1.083, 0.632 ± 0.274).

Fig. 3f: (0.622 ± 0.435, 1.954 ± 1.529) or (1.924 ± 1.064, 0.828 ± 0.559).

Fig. 3g: (0.801 ± 0.109, 1.251 ± 0.523) or (1.396 ± 0.249, 0.908 ± 0.313).

Fig. 3h: (0.775 ± 0.185, 1.692 ± 0.528) or (1.310 ± 0.281, 0.657 ± 0.263).

Fig. 3i: (1.060 ± 0.927, 1.381 ± 0.609) or (1.313 ± 0.585, 0.997 ± 0.829).

Fig. 3j: (0.976 ± 0.196, 1.060 ± 0.339) or (1.132 ± 0.256, 1.026 ± 0.318).

Fig. 4e: (0.353 ± 0.121, 3.973 ± 1.259) or (2.516 ± 0.675, 0.268 ± 0.064).

Fig. 4f: (0.521 ± 0.111, 2.444 ± 0.988) or (1.770 ± 0.434, 0.473 ± 0.193).

Fig. 4j: (0.488 ± 0.281, 3.221 ± 1.328) or (2.248 ± 0.981, 0.369 ± 0.182).

Fig. 4k: (0.345 ± 0.139, 4.957 ± 2.628) or (2.745 ± 0.820, 0.245 ± 0.103).

Fig. 4l: (0.662 ± 0.165, 2.035 ± 0.817) or (1.366 ± 0.329, 0.563 ± 0.220).

Fig. 5g: (0.374 ± 0.091, 3.650 ± 1.897) or (2.722 ± 1.498, 0.318 ± 0.111).

Fig. 5h: (0.531 ± 0.159, 3.468 ± 1.903) or (2.220 ± 1.032, 0.360 ± 0.163).