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Figure 1 | BMC Systems Biology

Figure 1

From: Huntington's disease: from experimental results to interaction networks, patho-pathway construction and disease hypothesis

Figure 1

Functional classification by cellular process of the proteins confirmed to be modulated in the DPEs. Numeric values indicate the number of proteins in each class. The results of MS identification using partially overlapping databanks (UniProt, and rat ENSEMBL+GENSCAN) were stored in a relational database designed in-house. Redundancy was removed and the lists of genes encoding the identified proteins were mapped on networks using MetaCore http://www.genego.com/metacore.php for analysis. In agreement with the experimental design, the apoptosis process is not present amongst the functional classes, while the "Stress response & Chaperones", "Energy metabolism" and "Proteasome degradation" are the best represented processes in the final results set.

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