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Figure 12 | BMC Systems Biology

Figure 12

From: Genetic and systems level analysis of Drosophila sticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks

Figure 12

sticky and dFmr1 mutant oocytes exhibit predicted axis polarity defects. (A-B) Phase contrast images of sticky+/- wild-type and dFmr1+/- wild-type, stage 14 oocytes showing normal dorsal/ventral axis formation as well as normal dorsal appendages. (C-E) Stage 14 stickyZ 3-5829/sticky3 (sticky-/-) and dFmr13/3 (dFmr1-/-) mutant oocytes are completely ventralized with missing or severely malformed dorsal appendages. Arrowheads point to regions of the oocytes where dorsal appendages would normally emanate.

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