Effect of ssRNA cleavage by Dicer on intracellular dynamics and infection patterns. Total Dicer cleavage rate is 10 cleavages per Dicer per hour and ΔSi = 4%. (A-C) measured intracellular +RNA levels from spatial model with Dicer cleavage rates: (A) 10 on dsRNA, 0 on ssRNA; (B) 8.5 on dsRNA, 1.5 on ssRNA; (C) 8.05 on dsRNA, 1.95 on ssRNA. (D-E) The infection patterns corresponding to (A-C). Shown are +RNA levels 300 hours post infection. (G) Bifurcation diagram of intracellular +RNA levels for increasing siRNA influx. The different lines are calculated with parameters from (A) black; (B) red; and (C) green. Circles indicate the position of 2 cells from the spatial model that reached the high or low equilibrium. (H and I) infection patterns showing +RNA levels corresponding to (B) and (C) 450 hours post infection. Colors according to the color-ramps in Figure 2.