Infection patterns with different types of amplification. (A) low double-strand Dicer cleavage rate (5 cleavages per Dicer per hour). Top row shows screen-shots for 1 siRNA per amplified transcript, bottom row 4 siRNAs per amplified transcript. siRNA movement is 4%. Amplification can reduce virus infection to mosaic or circle patterns, while it infected almost the entire tissue without amplification. (B-C) New patterns for intermediate double-strand Dicer cleavage rate (15 cleavages per Dicer per hour) and amplification. (B) zero siRNA movement results in a growing circle that leaves uninfected tissue behind; (C) 5% siRNA movement results in the appearance and disappearance of a spot. Parameters used: (B) primed amplification with 4 siRNAs per amplified transcript; (C) guided amplification with 4 siRNAs per amplified transcript. Colors according to the color-ramps shown in Figure 2.