Table 1 Parameter values used. #mol is number of molecules.
From: RNA silencing can explain chlorotic infection patterns on plant leaves
Model | Par. | Meaning | Value | units |
|---|---|---|---|---|
Intracellular | r | maximum translation rate × #ribosomes | 15*5000 | #mol hr-1 |
| Â | o | max rate of complex formation ssRNA | 1 | hr-1 |
| Â | o d | max rate of complex formation dsRNA | 100 | hr-1 |
| Â | f | ratio of binding plus or minus RNA | 0.9 | - |
| Â | h | dsRNA-RDR splitting rate | 10 | hr-1 |
| Â | v | max virion production rate | 500 | #mol hr-1 |
| Â | D i | number of Dicer molecules | 500 | #mol |
|  | c d | max Dicer cleavage rate for dsRNA | 0–15 | #mol hr-1 |
|  | c s | max Dicer cleavage rate for ssRNA | 0–10 | #mol hr-1 |
| Â | b 1 | rate of RISC activation | 0.005 | #mol -1 hr-1 |
| Â | b 2 | RISC target cleavage rate | 20 | #mol -1 hr-1 |
| Â | i | translation of RISC | 100 | #mol hr-1 |
| Â | a | amplification (a u , a p and a g ) | 100 | #mol hr-1 |
| Â | d r | decay RdRP and RISC | 0.1 | hr-1 |
| Â | D | decay viral ssRNA | 0.5 | hr-1 |
| Â | d si | decay siRNA | 2 | hr-1 |
| Â | d v | decay virions | 0.1 | hr-1 |
| Â | k v | saturation of virion production | 10,000 | #mol |
| Â | k d | saturation of Dicer cleavage | 10,000 | #mol |
| Â | k t | saturation constant for translation | 1,000 | #mol |
| Â | k ri | saturation of RISC cleavage | 1,000 | #mol |
| Â | k r | saturation of complex formation | 1,000 | #mol |
| Â | k a | saturation amplification | 1000 | #mol |
Spatial | ΔSi | percentage of siRNAs exiting the cell | 0–10 | hr-1 |
|  | ΔV | percentage of virions exiting the cell | 1 | hr-1 |
| Â | u | unpacking rate of virions | 2 | #mol hr-1 |