Modelling phagosomal lipid networks that regulate actin assembly

BMC Systems Biology

Table 2 Parameter estimation for the lipid network (sub-model II)

Parameter	units	Value	sensitivity (ΔlnSS/Δlnp)
V₁	1/min	0.00106	0.455
K_1ATP	μmol/l	159	0.354
V₂	μmol/(l*min)	0.0139	0.575
K_2ATP	μmol/l	62.9	0.424
K_2PIP	μmol/l	5.00	0.051
k₃	1/min	0.0175	0.361
k₄	1/min	0.0209	0.154
k₅	1/min	0.0226	0.454

The results of two independent experiments of ³²P-incorporation into lipids and the COPASI program were used to estimate parameters. Sensitivity for each parameter was calculated as explained in Methods.

ISSN: 1752-0509