Table 4 Targets in the H-List that are also involved in drug resistance mechanisms.
Resistance related proteins | |
|---|---|
Protein | Description |
CcdA (Rv0527) | Cytochrome |
PolA (Rv1629) | SOS |
LldD2 (Rv1872c) | Cytochrome |
QcrC (Rv2194) | Cytochrome |
QcrB (Rv2196) | Cytochrome |
CtaC (Rv2200c) | Cytochrome |
Cyp121 (Rv2276) | Cytochrome |
Rv3660c (Rv3660c) | HGT |
Proteins closely connected to resistance proteins | |
Protein | Closely connected to |
SecY (Rv0732) | DnaE1 (SOS) and SecA1 and SecA2 (HGT) |
Rv0843 (Rv0843) | Three cytochrome proteins |
Pdc (Rv0853c) | Rv1988 (Antibiotic Efflux Pump) and two cytochromes |
Rv1456c (Rv1456c) | Three cytochrome proteins |
Rv1711 (Rv1711) | RecA, DnaE1 (SOS proteins) and a cytochrome |
Rv1828 (Rv1828) | SecA2 (HGT) and two cytochromes |
QcrC (Rv2194) | Four cytochrome proteins |
QcrA (Rv2195) | Five cytochrome proteins |
QcrB (Rv2196) | Five cytochrome proteins |
CtaC (Rv2200c) | Five cytochrome proteins |
Cyp121 (Rv2276) | 19 cytochrome proteins |
HemE (Rv2678c) | Seven cytochrome proteins |
FtsK (Rv2748c) | SOS proteins RecA, PolA and DnaE1 |
RnhB (Rv2902c) | SOS proteins PolA, DnaE1 and DnaE2 |
TrmD (Rv2906c) | SOS proteins PolA, DnaE1 and Rv2294 (Antibiotic Efflux Pump) |
PrfB (Rv3105c) | PolA (SOS) and SecA1 and SecA2 (HGT) |
IlvX (Rv3509c) | Three cytochrome proteins |
TrxB2 (Rv3913) | RecA (SOS) and two cytochrome proteins |