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Table 1 The microorganisms and media conditions used in the study, together with the predicted gene essentiality results. The percentage of essential genes predicted correctly is a measure of how effective a screen the computational gene essentiality prediction really is.

From: Three factors underlying incorrect in silico predictions of essential metabolic genes

Organism Total # of genes Experimental media # of TP genes # of FN genes % essential genes correct
E. coli 1261 glucose MM 157 81 66.0
   glycerol MM 156 86 64.5
S. cerevisiae 750 glucose 63 95 39.9
   glucose (anaerobic) 47 109 30.1
   galactose 66 136 32.7
   glycerol 66 132 33.3
   ethanol 90 120 42.9
   rich 28 90 23.7
H. pylori 339 rich 36 39 48.0
S. aureus 619 rich (Forsyth et al.) 7 27 20.6
   rich (Ji et al.) 1 5 16.7
M. tuberculosis 661 Middlebrook 105 132 44.3
B. subtilis 844 rich 65 31 67.7