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Table 2 The connectivity of genes in the organisms studied. The overarching trend is that the mean connectivity of FN genes is less than the mean connectivity of TP genes for nearly all organisms and data sets.

From: Three factors underlying incorrect in silico predictions of essential metabolic genes

Organism

Overall Mean Connectivity

Experimental media

Mean connectivity of TP genes

Mean connectivity of FN genes

E. coli

2.97

glucose MM

2.13

2.15

  

glycerol MM

2.10

2.01

S. cerevisiae

1.80

glucose

2.38

1.36

  

glucose (anaerobic)

2.64

1.40

  

galactose

2.32

1.32

  

glycerol

2.36

1.31

  

ethanol

2.04

1.35

  

rich

3.39

1.44

H. pylori

1.36

rich

1.14

1.05

S. aureus

1.54

rich (Forsyth et al.)

1.29

1.04

  

rich (Ji et al.)

1.00

1.00

M. tuberculosis

1.72

Middlebrook

1.85

1.42

B. subtilis

1.96

rich

2.02

1.68