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Figure 2 | BMC Systems Biology

Figure 2

From: Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis

Figure 2

Graphic representation of the synthesis of tyrosine from chorismate. Yellow (resp. pink, green) boxes correspond to metabolites (resp. enzymes, transcription factors) pools. The black (resp. orange) arrows correspond to transcriptional/translational (resp. enzymatic) regulations. The effect of the regulation is indicated by the sign "-" in the case of a repression/inhibition, or by the sign "+" in the case of an induction/stimulation. A closed purple circle, associated with an enzyme, means that the gene(s) encoding the corresponding enzyme may be constitutively transcribed. An ellipse corresponds to a transcriptional regulator (transcription factor, T-box) that can be "on" (in green) or "off" (in red). The state "on" is defined as "able to bind to DNA". A hexagon represents a translational regulator that could also be "on" (in green) or "off" (in red). The translational regulator is defined as "on" when it is able to bind to mRNA.

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