Figure 3

Phase resetting properties of neurotransmitter driven coupled oscillators. A. Mean field of neurotransmitter for 200 coupled circadian oscillators entrained by a 12:12 light-dark cycle. The LD cycle is described by a square-wave forcing: L = 0 in dark phases and L = 1 in light phases. B. Phase response curve for 200 neurotransmitter coupled oscillators. Phase shifts in mean field generated by 1 h light treatments of intensity 1.0 are plotted against the circadian time at which the light pulses were given. Phase advances are plotted as positive values, and delays are plotted as negative values. C. 'Jet lag' experiment for 200 neurotransmitter coupled oscillators. Light dark cycle is advanced or delayed by 6 hours, and then phase difference is calculated by comparison to unperturbed system's phase in LD cycle. Light intensity in LD cycles = 1.0