Figure 5

a) A network graph of differentially expressed genes following Ifng treatment. A Pearson correlation cut-off of 0.9 was set to filter edges in the network and the resultant graph was clustered using the graph-based clustering algorithm MCL set at an inflation value of 2.2. Each node represents a transcript and nodes are coloured according to the cluster to which they belong. Nodes belonging to the same cluster share a common pattern of expression over the time-course following Ifng treatment. b) A view of the 26 clusters defined from the network graph in 5a. The size of each sphere representing a cluster corresponds to the size of its node membership. Clusters are assigned a description of the co-expression pattern they present over the time course and are coloured according to whether the nodes within those clusters are up-regulated (orange) or down-regulated (green) following the Ifng treatment.