Figure 9
From: A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway
Logarithmic amplification, LA (log units, see Equation 7.1), measured for different oscillatory stimuli. LA measures the signal amplification between pEpJ and DpS nc . The simulated data was averaged for several subsequent periods. The behaviour of the system was analysed for oscillatory stimuli with an average period duration T ∈ [0.5, 1440] minutes, and an average concentration of Epo osc ∈ [10-6, 10] units/ml. In all the simulations, the signal was averaged for 12 periods of the oscillatory stimulus.