From: Exploiting the pathway structure of metabolism to reveal high-order epistasis
Property | Brute-force LP (k = 2) | Random KO + Reduce (k = 10) | NetKO (k = 10) |
---|---|---|---|
Number of MCS found | 215 | 223 | 11,706 |
Highest Cardinality MCS Obtained | 2 | 3 | 10 |
Reactions included in at least one MCS | 263 | 235 | 355 |
Number of biomass components targeted | 38 | 41 | 36 |
Number of linear programming steps | 487,670 | 7,221,149 | 113,989 |