Figure 1

The Prodistin classification tree and the signalling PRODISTIN classes. The Drosophila PRODISTIN classification tree contains 472 Drosophila proteins. Protein names have been omitted for clarity. PRODISTIN classes containing signalling canonical proteins are coloured in magenta in the tree. Purple branches carry canonical proteins. Classes are named and numbered according to the signalling pathway's proteins they contain. When proteins from several pathways are present in the same class, the names of the different pathways are juxtaposed. For sake of clarity, the RAS cascade is clearly identified as such despite we didn't consider it as a pathway on its own. Details of the class proteins are shown in boxes using Flybase symbols for genes: canonical proteins are purple, non-canonical ones are magenta.