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Table 3 Analysis of flanking sequences (+/- 100 bp) around the 110 c-Myc binding sites

From: Transcription profiling of lung adenocarcinomas of c-myc-transgenic mice: Identification of the c-myc regulatory gene network

Matrix Hits in sequences (205 bp) of induced promoters Hits in sequences (205 bp) of control promoters Fold-Occurrence P-Wert
V$MYC_Q2 96 7 13.71 1.04731E-98
V$MYCMAX_01 16 4 4.00 2.00649E-06
V$MYCMAX_02 10 1 10.00 7.25446E-08
V$MYCMAX_B 18 2 9.00 1.73837E-12
V$MAX_01 34 6 5.67 4.50618E-17
V$EBOX_Q6_01 25 2 12.50 2.36615E-20
V$E2F_Q2 50 21 2.38 2.08371E-10
V$E2F1_Q3 22 7 3.14 1.12327E-06
V$E2F1_Q3_01 11 3 3.67 0.000171353
V$E2F1_Q6 11 5 2.20 0.007294131
V$AP2_Q6 17 7 2.43 0.000392586
V$AP2_Q6_01 14 5 2.80 0.000339388
V$AP2ALPHA_03 30 8 3.75 1.41269E-10
V$AP2GAMMA_01 21 2 10.50 1.04239E-15
V$ZF5_B 85 37 2.30 7.71777E-21
V$ZIC3_01 22 10 2.20 0.000213134
  1. The TRANSFAC identifier of the respective matrix, the number of hits in the 110 different sequences (205 bp) of induced gene promoters, the number of hits in the 110 different sequences (205 bp) of control (non-regulated) gene promoters, and the corresponding fold occurrences are given in this table. The occurrence value of the respective binding site in the promoters of control genes is set to 1. Significance of the representation value of binding sites in flanking sequences (+/- 100 bp) around the 110 c-Myc binding sites in the promoters of induced genes is measured by the p-value derived from the binomial distribution.