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Table 1 Significantly enriched or depleted GO terms.

From: Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion

Enriched GO terms
Category GO.ID GO.Term P value
BP 7169 transmembrane receptor protein tyrosine kinase signaling pathway 0.000108
  6069 ethanol oxidation 0.004402
  30183 B cell differentiation 0.004668
  8285 negative regulation of cell proliferation 0.004690
  6641 triacylglycerol metabolism 0.005847
  42592 Homeostasis 0.009063
  6631 fatty acid metabolism 0.009442
CC 118 histone deacetylase complex 0.001873
  5578 extracellular matrix (sensu Metazoa) 0.008284
MF 16566 specific transcriptional repressor activity 0.001047
  15248 sterol transporter activity 0.004570
  4024 alcohol dehydrogenase activity, zinc-dependent 0.004699
  4407 histone deacetylase activity 0.006790
  4300 enoyl-CoA hydratase activity 0.008276
  3700 transcription factor activity 0.008297
  8484 sulfuric ester hydrolase activity 0.008613
  5518 collagen binding 0.009071
  4924 oncostatin-M receptor activity 0.009582
Depleted GO terms
Category GO.ID GO.Term P value
BP 6959 humoral immune response 0.000405
  6356 regulation of transcription from RNA polymerase I promoter 0.002046
  15986 ATP synthesis coupled proton transport 0.004346
  1701 embryonic development (sensu Mammalia) 0.004439
  30187 melatonin biosynthesis 0.006552
  6906 vesicle fusion 0.007231
  7286 spermatid development 0.008267
  31424 Keratinization 0.008692
  17148 negative regulation of protein biosynthesis 0.009817
CC 16469.00 proton-transporting two-sector ATPase complex 0.002401
  19898.00 extrinsic to membrane 0.006794
MF 16165 lipoxygenase activity 0.000954
  4111 creatine kinase activity 0.003959
  46933 hydrogen-transporting ATP synthase activity, rotational mechanism 0.004516
  46961 hydrogen-transporting ATPase activity, rotational mechanism 0.004516
  4983 neuropeptide Y receptor activity 0.004746
  8048 calcium sensitive guanylate cyclase activator activity 0.005498
  17096 acetylserotonin O-methyltransferase activity 0.006552
  4857 enzyme inhibitor activity 0.007804
  15232 heme transporter activity 0.009458