Table 1 Significantly enriched or depleted GO terms.
From: Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion
| Enriched GO terms | |||
|---|---|---|---|
| Category | GO.ID | GO.Term | P value |
| BP | 7169 | transmembrane receptor protein tyrosine kinase signaling pathway | 0.000108 |
| 6069 | ethanol oxidation | 0.004402 | |
| 30183 | B cell differentiation | 0.004668 | |
| 8285 | negative regulation of cell proliferation | 0.004690 | |
| 6641 | triacylglycerol metabolism | 0.005847 | |
| 42592 | Homeostasis | 0.009063 | |
| 6631 | fatty acid metabolism | 0.009442 | |
| CC | 118 | histone deacetylase complex | 0.001873 |
| 5578 | extracellular matrix (sensu Metazoa) | 0.008284 | |
| MF | 16566 | specific transcriptional repressor activity | 0.001047 |
| 15248 | sterol transporter activity | 0.004570 | |
| 4024 | alcohol dehydrogenase activity, zinc-dependent | 0.004699 | |
| 4407 | histone deacetylase activity | 0.006790 | |
| 4300 | enoyl-CoA hydratase activity | 0.008276 | |
| 3700 | transcription factor activity | 0.008297 | |
| 8484 | sulfuric ester hydrolase activity | 0.008613 | |
| 5518 | collagen binding | 0.009071 | |
| 4924 | oncostatin-M receptor activity | 0.009582 | |
| Depleted GO terms | |||
| Category | GO.ID | GO.Term | P value |
| BP | 6959 | humoral immune response | 0.000405 |
| 6356 | regulation of transcription from RNA polymerase I promoter | 0.002046 | |
| 15986 | ATP synthesis coupled proton transport | 0.004346 | |
| 1701 | embryonic development (sensu Mammalia) | 0.004439 | |
| 30187 | melatonin biosynthesis | 0.006552 | |
| 6906 | vesicle fusion | 0.007231 | |
| 7286 | spermatid development | 0.008267 | |
| 31424 | Keratinization | 0.008692 | |
| 17148 | negative regulation of protein biosynthesis | 0.009817 | |
| CC | 16469.00 | proton-transporting two-sector ATPase complex | 0.002401 |
| 19898.00 | extrinsic to membrane | 0.006794 | |
| MF | 16165 | lipoxygenase activity | 0.000954 |
| 4111 | creatine kinase activity | 0.003959 | |
| 46933 | hydrogen-transporting ATP synthase activity, rotational mechanism | 0.004516 | |
| 46961 | hydrogen-transporting ATPase activity, rotational mechanism | 0.004516 | |
| 4983 | neuropeptide Y receptor activity | 0.004746 | |
| 8048 | calcium sensitive guanylate cyclase activator activity | 0.005498 | |
| 17096 | acetylserotonin O-methyltransferase activity | 0.006552 | |
| 4857 | enzyme inhibitor activity | 0.007804 | |
| 15232 | heme transporter activity | 0.009458 | |