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Table 2 Target genes that shRNA were significantly enriched.

From: Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion

Gene P-value T-statistics Entrez Gene Significant GO term GO category shRNA sequence
EDN2 0.0011 20.9528 1907 transmembrane receptor protein tyrosine kinase signaling pathway BP 5'AGCTCTGCTGGAAGA ACTGCATGGGGA3'
ARNTL2 0.0020 15.7851 56938 transcription factor activity MF 5'TTACCTTGTAGCTCT CAATCATCAGAA3'
ZNF232 0.0030 12.7514 7775 transcription factor activity MF 5'TATAACTCACATCT TGTTGTCCACCAG3'
ADH5 0.0040 11.1071 128 ethanol oxidation BP 5'GTATAACCTAAACC ATCTACTCTTTAG3'
COL15A1 0.0043 10.7380 1306 extracellular matrix (sensu Metazoa) CC 5'GCAACTGCTGTTCGT ACACAGAAACAG3'
EMP3 0.0071 8.2852 2014 negative regulation of cell proliferation BP 5'TGAATCTCTGGTACG ACTGCACGTGGA3'
MYT2 0.0072 8.2309 8827 transcription factor activity MF 5'AAGCAGATGATATT CCAGACGGTATTA3'
ZNF219 0.0079 7.8689 51222 transcription factor activity MF 5'GGTAGTGGGCCCTCA GGGGCGATTAGC3'
IL6ST 0.0080 7.8232 3572 oncostatin-M receptor activity MF 5'TGTCCAGTATTCTAC CGTGGTACACAG3'
MEOX2 0.0080 7.8013 4223 transcription factor activity MF 5'GCACTCACAATGACA ACCAGAGCCAGT3'
EPHB4 0.0092 7.2683 2050 transmembrane receptor protein tyrosine kinase signaling pathway BP 5'TTCTACCGTCCTTGT CATAACTTTGTG3'
KLF10 0.0093 7.2104 7071 negative regulation of cell proliferation; transcription factor activity BP/MF 5'ATTGGGTGTAGATTT CTGACATCAAAA3'
TFEC 0.0097 7.0622 22797 transcription factor activity MF 5'GCTATGCAATTATGC TCTGTGTTTCAT3'
NPC1 0.0098 7.0363 4864 sterol transporter activity MF 5'GATGCTCTCATAAGG CCCAGGAAGGAT3'