Figure 4From: Time-resolved metabolomics reveals metabolic modulation in rice foliageHierarchical cluster analysis. A. Cluster analysis (Ward's method [26]) was applied to the correlation matrix composed of metabolic intermediates in the glycolytic pathway. The generated dendrogram was clustered into regulatory units by the ATP/ADP ratio; hexokinase (EC 2.7.1.1), phosphoglycerate kinase (EC 2.7.2.3), and pyruvate kinase (EC 2.7.1.40). B. As well as in the TCA cycle, the dendrogram was divided into two major groups at the rate-limiting steps; citrate synthase (CS; EC 2.3.3.1), and NADP-dependent isocitrate dehydrogenase (ICDH; EC 1.1.1.42).Back to article page