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Figure 4 | BMC Systems Biology

Figure 4

From: Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targets

Figure 4

Dynamic protein-protein interactions in caspase formation. (A) Protein-protein interactions within the hub caspases of cancer cells during 0–8 hours after induction of apoptosis. Distinct interactions at different times are marked with bold lines. (B) During 4–30 hours after induction of apoptosis in cancer cells. (C) During 0–8 hours after induction of apoptosis in normal cells. (D) During 4–36 hours after induction of apoptosis in normal cells (see Supplementary Tables 5 and 6).

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