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Table 2 Average confidence values for directed edge features for the 7 highest-confidence gene pairs derived from the Golub et al. data [17] in a BN analysis using no prior seeds or priors derived from the literature. The t-test p-value measures the likelihood that prior and no-prior results are equivalent.

From: Seeded Bayesian Networks: Constructing genetic networks from microarray data

Gene pairs

Average no prior

Average prior

t-test p-value

SMARCA4

SMARCA4_2

0.4075

0.959583

0.001059

CBX1

SRP9

0.155833

0.944583

1.18 × 10-6

TMPO

GTF2E2

0.017083

0.934583

6.54 × 10-10

SMARCA4_2

RBBP4

0.005833

0.894583

7.67 × 10-8

CD79A

DHPS

0.011667

0.894167

1.32 × 10-7

FAH

MCM3

0.02375

0.877083

5.90 × 10-7

FAH

PSMA6

0.02875

0.790833

5.80 × 10-6