The colon cancer-specific gene network. The network was made manually by integrating 109 significant gene-gene interactions among 52 known genes. The functional category "regulation of physiological process" was highlighted with green shadow. Five centres defined by IL8, DES, RPL30, RBM9 and ENO1 were made to be easily visualized. The colour or shape coding of the entities was the same as used in PathwayAssist, as indicated by the bottom bar.