Figure 1
From: Parameter estimation and determinability analysis applied to Drosophila gap gene circuits
A graphical representation of the confidence region in the 2-dimensional case. a) Example of a fitness landscape S(θ) for a linear model and the contours corresponding to different confidence regions. b) Example of an ellipsoidal confidence region and an accuracy sphere, where principal axes of the ellipsoid, z1 and z2, define the new coordinate system which is a rotation of actual parameter space (θ1; θ2). Clearly, z1 is well-determined, while z2 is not.