Parameter estimation and determinability analysis applied to Drosophila gap gene circuits

BMC Systems Biology

Table 1 RMS distribution for parameter estimates.

	RMS < 10.0	10.0 ≤ RMS < 12.0	12.0 ≤ RMS < 14.0	RMS ≥ 14.0
θ ⁱⁿ	5	36	21	18
${\hat{θ}}_{f u l l}$	71	3	1	5
${\hat{θ}}_{f i x e d}$	63	7	2	8

Entries in the table show the number of parameter estimates with corresponding ranges for RMS, where θⁱⁿcorrespond to initial parameter estimate; ${\hat{θ}}_{f u l l}$ and ${\hat{θ}}_{f i x e d}$ correspond to the parameter estimates after using the LM method in the full search case and the case of fixed promoter thresholds, respectively.

ISSN: 1752-0509