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Figure 3 | BMC Systems Biology

Figure 3

From: Robust simplifications of multiscale biochemical networks

Figure 3

Lipniacki's model a) Testing quasistationarity: nonreduced trajectories (solid), quasi-stationarity trajectories (crosses). b) Trajectories of models in the hierarchy. c) Cytoplasmatic part of the signalling mechanism: terminal species (blue), intermediate species quasi-stationary (pink) non-oscillating (green), simple submechanisms (blue). This part of the network contains three critical parameters for the damping time. Sustained oscillations were obtained by decreasing the constant k3 ten times with respect to the value used in [53] (equivalently, this can be obtained by decreasing k9, or by increasing k4).

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