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Figure 2 | BMC Systems Biology

Figure 2

From: Simulating in vitro transcriptional response of zinc homeostasis system in Escherichia coli

Figure 2

Simulation of Zur-DNA interaction. The black dots are reconstructed from the reported data in the original figure (the right graph in Fig. 3 in [22]) using image analysis method (please refer to the Methods for more details). The black curve is the simulated ratio (i.e., Q w 2 s MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemyuaeLaem4DaC3aa0baaSqaaiabikdaYaqaaiabdohaZbaaaaa@3105@ /D0 * 100%) of the final steady state concentration values of Zn4Zur-DNA complex (denoted by Q w 2 s MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemyuaeLaem4DaC3aa0baaSqaaiabikdaYaqaaiabdohaZbaaaaa@3105@ ) and the total concentration of DNA (D0 = 1 nM in this case) as a function of the logarithm of parameter Zn which denotes the simulated free zinc concentration.

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