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Table 5 Different transient responses of the MAPK network

From: Dynamical pathway analysis

  BRAF to MAP2K2 BRAF to MAPK1
Wild type RiseTime: 31.5 RiseTime: 0.26
  SettlingTime: 56.5 SettlingTime: 76.1
  Overshoot: 0 Overshoot: 440.4
R73A Mutant RiseTime: 2.6 RiseTime: 8.2
  SettlingTime: 5.8 SettlingTime: 17.0
  Overshoot: 0 Overshoot: 0
R80A Mutant RiseTime: 11.7 RiseTime: 48.5
  SettlingTime: 21.7 SettlingTime: 90.2
  Overshoot: 0 Overshoot: 0