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Figure 6 | BMC Systems Biology

Figure 6

From: Dynamics of receptor and protein transducer homodimerisation

Figure 6

Comparison of single and double activation. Comparison between single protein (rSA) and double protein (rDA) activation rates for the interval of feasible values of inactive protein P. Normalised units were used in this comparison (P = 1 is total amount of available protein). Figure 6 [a]: Comparison of the three possible cases. In solid black we represents the value of the single activation signal rate (rSA) for k1 = 0.3 in the interval of feasible values of P (0.0 ≤ P ≤ 1.0). The dashed line represents double activation rate (rDA) when both rate constants are identical (k3 = k1). Upward triangles represent the double activation rate when k3 > k1 and downward triangles when k3 <k1. Figure 6 [b]: Only with k3 > k1 the double protein activation dominates but for high protein concentrations. The concentration of P in which contributions from both single and dual activation signal rates are identical is called Peq = k1/k3 and is represented with a finely dashed line.

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