Figure 7From: Dynamics of receptor and protein transducer homodimerisationDynamic simulation. Dynamical simulation of the system when dual mechanism and asymmetric deactivation of the receptor are assumed. The dynamics of the protein was complemented with a rate describing de deactivation and break down of the homodimeric protein P*P* ( r P ∗ P deact ∗ MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemOCai3aaSbaaSqaaiabdcfaqnaaCaaameqabaGaey4fIOcaaSGaemiuaa1aa0baaWqaaiabbsgaKjabbwgaLjabbggaHjabbogaJjabbsha0bqaaiabgEHiQaaaaSqabaaaaa@38B5@ = k4·P*P*). Figure 7 [a]: Time course for the relevant variables of the system: monomeric activated protein (P*), fully activated receptor (R*R*) and partially activated receptor (R*R). Figure 7 [b]: Time course for single (rSA) and double (rDA) protein activation rates during the simulation. Initial conditions: P(0) = 1.0; P*(0) = 0.0; R*R*(0) = 0:5; R*R(0) = 0.0. Parameter values: k1 = 0.02; k2 = 0 > 05; k3 = 5*k1 = 0.1; k4 = 0.0125; kD1 = kD2 = 0.01.Back to article page