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Table 1 Probability rates for positive autogenous circuit

From: Genetic noise control via protein oligomerization

Category Symbol Reaction Value (s-1) Ref.
protein dimerization k 1 P1 + P1 → P2 0.001–0.1 [51, 52]
  q 1 P2 → P1 + P1 0.1–1  
TF-operator int k 20 P2 + D00 → D20 0.012 [5355]
  q 20 D20 → P2 + D00 0.9  
  k 21 P1 + D00 → D10 0.038  
  q 21 D10 → P1 + D00 0.3  
  k 22 P1 + D10 → D20 0.011  
  q 22 D20 → P1 + D10 0.9  
RNAp-promoter int k 30 R + D00 → D01 0.038 [5658]
  q 30 D01 → R + D00 0.3  
  k 31 R + D10 → D11 0.038, 0.38  
  q 31 D11 → R + D10 0.3, 0.03  
  k 32 R + D20 → D21 0.38*†  
  q 32 D21 → R + D20 0.03*†  
Isomerization ν Dx1 → C + Dx0 0.0078 [55]
tsx-tsl elongation & decay α C → M + R 0.03 [59, 60]
  β M → P1 + M 0.044  
  γ 0 M → 0.0039  
  γ 1 P1 7 × 10-4  
  γ 2 P2 0.7–3.5 × 10-4  
  1. Kinetic rates for the positive autogenous circuit. Experimentally available rates are all taken from lambda phage-E. coli complex. The values with superscript correspond to the circuit topologies DA1 (*), DA2 (†), and DA3 (‡) in Fig. 1.