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Table 3 Pearson correlations (r) between the expression profiles of the 20 candidate genes from the IWGCNA and MEblue, CFS severity, and the TPH2 SNP.

From: Integrated Weighted Gene Co-expression Network Analysis with an Application to Chronic Fatigue Syndrome

  Candidate Genes from IWGCNA: Gene Name and Genbank Accession Pearson correlations with gene expression profiles
   MEblue CFS Severity TPH2 SNP
   r: All Rank* r: All p-value r: M r: F r: All p-value r: M r: F
1 FOXN1 (NM_003593) 0.845 195 0.21 0.055 0.27 0.21 0.21 0.018 0.23 0.20
2 PRDX3 (AF118073) 0.848 181 0.26 0.017 0.43 0.21 0.21 0.020 0.32 0.17
3 SUCLA2 (AK001458) 0.844 197 0.20 0.059 0.25 0.18 0.20 0.021 0.36 0.17
4 DCTN2 (NM_006400) 0.909 30 0.18 0.087 0.21 0.16 0.23 0.009 0.41 0.18
5 PGK1 (AB062432) 0.849 176 0.22 0.045 0.37 0.21 0.14 0.108 0.26 0.12
6 SNURF (AF101044) 0.882 77 0.27 0.012 0.51 0.20 0.18 0.037 0.32 0.14
7 PRKCH (BC001000) 0.888 64 0.16 0.143 0.27 0.14 0.15 0.089 0.23 0.13
8 RYK (NM_002958) 0.867 113 0.21 0.048 0.26 0.20 0.12 0.182 0.21 0.09
9 PPP1R14C (AF407165) 0.866 114 0.24 0.025 0.21 0.25 0.21 0.016 0.26 0.19
10 VAMP5 (AF077197) 0.863 124 0.33 0.002 0.47 0.29 0.24 0.007 0.35 0.20
11 PRO0641 (AF090939) 0.853 159 0.32 0.003 0.43 0.30 0.21 0.016 0.25 0.19
12 TMEM50A (AF081282) 0.911 23 0.26 0.014 0.29 0.26 0.17 0.050 0.22 0.16
13 CRNKL1 (AF111802) 0.865 117 0.27 0.012 0.41 0.23 0.22 0.013 0.36 0.18
14 NPAL2 (AK024017) 0.919 10 0.35 0.001 0.37 0.35 0.21 0.020 0.33 0.16
15 TFB2M (AK026314) 0.899 49 0.31 0.004 0.29 0.31 0.21 0.016 0.22 0.19
16 PBLD (AK027673) 0.906 38 0.31 0.003 0.28 0.34 0.17 0.049 0.23 0.15
17 LTV1 (AK027815) 0.856 145 0.30 0.005 0.39 0.29 0.19 0.029 0.29 0.17
18 MED8 (BC010019) 0.869 108 0.29 0.007 0.31 0.28 0.22 0.015 0.35 0.18
19 CD302 (BC020646) 0.817 315 0.24 0.028 0.28 0.25 0.18 0.046 0.29 0.16
20 (XM13557) 0.887 68 0.32 0.002 0.36 0.29 0.19 0.032 0.38 0.15
  Median: 0.866 114 0.27 0.013 0.30 0.25 0.21 0.021 0.29 0.17
  1. The correlations were computed using all 127 samples studied (All), the 98 female samples and the 29 male samples except for the correlation with severity which only had 87 non-missing scores (64 female and 23 male). The CFS Severity column is bolded for clarity.
  2. *The rank of each gene in terms of its MEblue correlation out of the 8966 genes used to start the analysis.