Table 4 Candidate gene names and Entrez Gene descriptions from the standard analysis.
Gene Name and Genbank Accession | Gene name. Entrez Gene and/or GeneRIFs description. Chromosome Location | |
|---|---|---|
1 | DGCR8 (AF165527) | DiGeorge syndrome critical region gene 8. 22q11.2 |
2 | PPARD (BC002715) | Peroxisome proliferator-activated receptor delta. May be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. 6p21.2-p21.1 |
3 | IHPK2 (BC004469) | Inositol hexaphosphate kinase 2. May affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. 3p21.31 |
4 | CCDC92 (AB015292) | Coiled-coil domain containing 92. 12q24.31 |
5 | NR5A2 (AB019246) | Nuclear receptor subfamily 5, group A, member 2. May be involved in regulation of Hepatitis B virus. 1q32.1 |
6 | PDPK1 (BC006339) | 3-phosphoinositide dependent protein kinase-1. 16p13.3 |
7 | NXF1 (AF112880) | Nuclear RNA export factor 1. Exports viral mRNA's and herpes simplex virus type 1. 11q12-q13 |
8 | COL13A1 (NM_080804) | Collagen, type XIII, alpha 1. May function in connective tissues. 10q22 |
9 | AXIN2 (AF078165) | Regulates stability of beta-catenin in the Wnt signaling pathway. Mutations associated with colorectal cancer. 17q23-q24 |
10 | SCAP (AK075528) | SREBF chaperone. Involved in regulating sterol biosynthesis. 3p21.31 |
11 | DFFA (AF087573) | DNA fragmentation factor, 45 kDa, alpha polypeptide. Triggers DNA fragmentation during apoptosis. 1p36.3-p36.2 |
12 | TCF4 (M74719)* | Transcription factor 7-like 2 (T-cell specific, HMG-box). Implicated in blood glucose homeostasis. 10q25.3 |
13 | WNT16 (NM_016087) | Wingless-type MMTV integration site family, member 16. Implicated in oncogenesis and in several developmental processes. 7q31 |
14 | ZNF687 (BC032463) | Zinc finger protein 687. 1q21.2 |
15 | FGF1 (BC032697) | Fibroblast growth factor 1 (acidic). Embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. 5q31 |
16 | ANKRD6 (BC001078)* | Ankyrin repeat domain 6. 6q14.2-q16.1 |
17 | EPHX1 (M36374) | Epoxide hydrolase 1, microsomal (xenobiotic). Activation and detoxification of exogenous chemicals such as polycyclic aromatic hydrocarbons. 1q42.1 |
18 | FAIM (AK001444) | Fas apoptotic inhibitory molecule. 3q22.3 |
19 | ZMYND11 (NM_006624) | Zinc finger, domain containing 11. Binds adenovirus E1A protein. 10p14 |
20 | ADFP (NM_001122) | Adipose differentiation-related protein. 9p22.1 |
21 | BAT5 (BC031839) | HLA-B associated transcript 5. Possibly involved in immunity. 6p21.3 |
22 | CEBPA (NM_004364) | CCAAT/enhancer binding protein, alpha. Body weight homeostasis. 19q13.1 |
23 | HNRNPA1 (NM_002136) | Heterogeneous nuclear ribonucleoprotein A1. May be part of the regulatory mechanisms of the life cycle of HTLV-1 human retrovirus in T cells. 12q13.1 |
24 | DMBT1 (NM_004406) | Deleted in malignant brain tumors 1. May play a role in the interaction of tumor cells and the immune system. 10q25.3-q26.1 |
25 | RNASEN (AF116910) | Ribonuclease type III, nuclear. Participates in diverse RNA maturation and decay pathways. 5p13.3 |
26 | EDAR (AF130988) | Ectodysplasin A receptor. Mutations in this gene result in hypohidrotic ectodermal dysplasia. 2q11-q13 |
27 | F3 (AF540377) | Coagulation factor III (thromboplastin, tissue factor). Enables cells to initiate the blood coagulation cascades. 1p22-p21 |
28 | HSPG2 (AL445795) | Heparan sulfate proteoglycan 2. 1p36.1-p34 |
29 | EIF2C2 (AF121255) | Eukaryotic translation initiation factor 2C, 2. Encodes a member of the Argonaute family of proteins which play a role in RNA interference. 8q24 |