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Table 4 Candidate gene names and Entrez Gene descriptions from the standard analysis.

From: Integrated Weighted Gene Co-expression Network Analysis with an Application to Chronic Fatigue Syndrome

Gene Name and Genbank Accession Gene name. Entrez Gene and/or GeneRIFs description. Chromosome Location
1 DGCR8 (AF165527) DiGeorge syndrome critical region gene 8. 22q11.2
2 PPARD (BC002715) Peroxisome proliferator-activated receptor delta. May be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. 6p21.2-p21.1
3 IHPK2 (BC004469) Inositol hexaphosphate kinase 2. May affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. 3p21.31
4 CCDC92 (AB015292) Coiled-coil domain containing 92. 12q24.31
5 NR5A2 (AB019246) Nuclear receptor subfamily 5, group A, member 2. May be involved in regulation of Hepatitis B virus. 1q32.1
6 PDPK1 (BC006339) 3-phosphoinositide dependent protein kinase-1. 16p13.3
7 NXF1 (AF112880) Nuclear RNA export factor 1. Exports viral mRNA's and herpes simplex virus type 1. 11q12-q13
8 COL13A1 (NM_080804) Collagen, type XIII, alpha 1. May function in connective tissues. 10q22
9 AXIN2 (AF078165) Regulates stability of beta-catenin in the Wnt signaling pathway. Mutations associated with colorectal cancer. 17q23-q24
10 SCAP (AK075528) SREBF chaperone. Involved in regulating sterol biosynthesis. 3p21.31
11 DFFA (AF087573) DNA fragmentation factor, 45 kDa, alpha polypeptide. Triggers DNA fragmentation during apoptosis. 1p36.3-p36.2
12 TCF4 (M74719)* Transcription factor 7-like 2 (T-cell specific, HMG-box). Implicated in blood glucose homeostasis. 10q25.3
13 WNT16 (NM_016087) Wingless-type MMTV integration site family, member 16. Implicated in oncogenesis and in several developmental processes. 7q31
14 ZNF687 (BC032463) Zinc finger protein 687. 1q21.2
15 FGF1 (BC032697) Fibroblast growth factor 1 (acidic). Embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. 5q31
16 ANKRD6 (BC001078)* Ankyrin repeat domain 6. 6q14.2-q16.1
17 EPHX1 (M36374) Epoxide hydrolase 1, microsomal (xenobiotic). Activation and detoxification of exogenous chemicals such as polycyclic aromatic hydrocarbons. 1q42.1
18 FAIM (AK001444) Fas apoptotic inhibitory molecule. 3q22.3
19 ZMYND11 (NM_006624) Zinc finger, domain containing 11. Binds adenovirus E1A protein. 10p14
20 ADFP (NM_001122) Adipose differentiation-related protein. 9p22.1
21 BAT5 (BC031839) HLA-B associated transcript 5. Possibly involved in immunity. 6p21.3
22 CEBPA (NM_004364) CCAAT/enhancer binding protein, alpha. Body weight homeostasis. 19q13.1
23 HNRNPA1 (NM_002136) Heterogeneous nuclear ribonucleoprotein A1. May be part of the regulatory mechanisms of the life cycle of HTLV-1 human retrovirus in T cells. 12q13.1
24 DMBT1 (NM_004406) Deleted in malignant brain tumors 1. May play a role in the interaction of tumor cells and the immune system. 10q25.3-q26.1
25 RNASEN (AF116910) Ribonuclease type III, nuclear. Participates in diverse RNA maturation and decay pathways. 5p13.3
26 EDAR (AF130988) Ectodysplasin A receptor. Mutations in this gene result in hypohidrotic ectodermal dysplasia. 2q11-q13
27 F3 (AF540377) Coagulation factor III (thromboplastin, tissue factor). Enables cells to initiate the blood coagulation cascades. 1p22-p21
28 HSPG2 (AL445795) Heparan sulfate proteoglycan 2. 1p36.1-p34
29 EIF2C2 (AF121255) Eukaryotic translation initiation factor 2C, 2. Encodes a member of the Argonaute family of proteins which play a role in RNA interference. 8q24
  1. *Members of the blue module.