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Figure 2 | BMC Systems Biology

Figure 2

From: Investigating the robustness of the classical enzyme kinetic equations in small intracellular compartments

Figure 2

Deviations from the predictions of the MM equation for diffusion-mediated substrate transport. (Model I) Plot of the Percentage Error in reaction velocity, R p = 100|1 -α M /α|, versus the normalized reaction velocity of the MM equation, α M for 10 enzymes (green) and 100 enzymes (red) with K M = 10 μM in compartments with diameter 100 nm (A) and 50 nm (B). The solid lines show the theoretical predictions, as encapsulated by Eqs. (7) and (8); the data points are obtained by stochastic simulation (see Methods for details).

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