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Table 1 Summary of the ReTrace [21] analysis of the amino acid biosynthetic routes in T. reesei.

From: 13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose

Amino acid

Precursors

Paths

Zo

AvgSc

BestSize

AvgSize

MinPoor

Ala

Pyr

227

1

652

1

16.8

0

Arg

Oga

134

1

811

9

15.1

0

Asp

Oaa

121

1

757

1

13.5

0

Glu

Oga

36

1

426

1

12.6

0

Gly

Ser

260

1

1128

1

16.1

0

Gly

Thr

71

1

522

2

12.6

0

His

R5P

21

1

774

22

25.8

0

Ile

OAA, Pyr

483

1

797

14

18.7

0

Leu

AcCoA, Pyr

916

1

356

13

19.1

1

Lys

AcCoA, Oga

347

0.67

834

11

14.6

0

Phe

E4P, PEP

348

1

679

12

19.2

0

Pro

Oga

119

1

673

3

14.4

0

Ser

3PG

69

1

670

3

15.3

0

Thr

Oaa

97

1

768

7

2.5

0

Tyr

E4P, PEP

156

1

654

19

19.6

0

  1. Paths paths found, Zo highest fraction of transferred atoms, AvgSc average reaction scores, BestSize the size of the pathway achieving Zo reported, AvgSize average pathway size, MinPoor minimum number of reactions with a score under 50