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Table 1 Overrepresented GO biological processes in genes downregulated on 2nd day of PTZ treatment

From: A Drosophila systems model of pentylenetetrazole induced locomotor plasticity responsive to antiepileptic drugs

GO_ID

TERM

P_VALUE

GO:0000902

cell morphogenesis

1.09E-16

GO:0030154

cell differentiation

1.41E-11

GO:0051179

localization

3.35E-11

GO:0007154

cell communication

7.58E-09

GO:0019226

transmission of nerve impulse

9.01E-09

GO:0006810

transport

1.15E-08

GO:0007267

cell-cell signaling

1.18E-08

GO:0007268

synaptic transmission

1.74E-08

GO:0007399

nervous system development

2.30E-07

GO:0019219

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

2.55E-06

GO:0001505

regulation of neurotransmitter levels

3.93E-06

GO:0022008

neurogenesis

5.55E-06

GO:0048666

neuron development

1.70E-05

GO:0030030

cell projection organization and biogenesis

2.57E-05

GO:0048699

generation of neurons

5.83E-05

GO:0031175

neurite development

6.86E-05

GO:0030182

neuron differentiation

0.0001055

GO:0007269

neurotransmitter secretion

0.0003908

GO:0007010

cytoskeleton organization and biogenesis

0.0006173

GO:0016070

RNA metabolic process

0.0006893

GO:0008104

protein localization

0.0008227

GO:0007626

locomotory behavior

0.0009849

GO:0007409

axonogenesis

0.0011489

GO:0006464

protein modification process

0.0027655

GO:0007155

cell adhesion

0.0030866

GO:0045449

regulation of transcription

0.0043652

GO:0043687

post-translational protein modification

0.005309

GO:0048489

synaptic vesicle transport

0.0067834

GO:0016477

cell migration

0.0075502

GO:0006928

cell motility

0.0102359

GO:0007411

axon guidance

0.0141982

GO:0007517

muscle development

0.0142275

GO:0046530

photoreceptor cell differentiation

0.0197214

GO:0001754

eye photoreceptor cell differentiation

0.0297998

GO:0048512

circadian behavior

0.0376882

GO:0008361

regulation of cell size

0.0383864

  1. Some non-specific processes are not shown. For details, see text. p values are after Bonferroni correction.