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Figure 3 | BMC Systems Biology

Figure 3

From: Detecting coordinated regulation of multi-protein complexes using logic analysis of gene expression

Figure 3

Illustration of triplet logic relationships in which the regulation of a third gene is strongly correlated to some combined regulation of two other genes. Each circle represents a single mRNA profile readout and its position indicates whether the expression of A and B are regulated. A filled circle implies that C is regulated, while an empty circle implies C is non-regulated. Tables I. and II. describe the two logic patterns that were analyzed in this study. Below each table is the logic statement and associated text. Each gene can be in three possible states: induced, repressed or unregulated. This expands the number of logical relationships we see. I.) The case of regulated expression described by the AND logic statement. We have eight possible different regulatory states for logic statement AND as shown in the figure. II.) The case of regulated expression described by the XOR logic statement. For this logic statement we also have eight possible regulatory states.

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