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Table 1 Statistical analysis of iHSLN biological functions.

From: Human synthetic lethal inference as potential anti-cancer target gene detection

GO term - Biological function P-value % of genes in iHSLN % of genes in GOA
DNA replication 5.20 E-28 6.8 40.9
DNA repair 4.93 E-24 7.4 27.7
Response to DNA damage stimulus 4.00 E-23 8.1 24.9
RNA processing 4.56 E-15 8.7 17.9
Cell cycle 2.50 E-13 9.8 15.7
Proteasomal protein catabolic process 1.10 E-8 24.0 30
Golgi vesicle transport 1.70 E-8 25.0 28.4
  1. The columns include: Column 1 - the biological function from GOA; column 2 - the P-value associated to the results; column 3 - the percentage of genes with a given GO term encountered in iHSLN (998 genes); column 4 - the percentage of genes with a given GO term encountered in GOA (14486 genes) (see Additional file 1).