From: Human synthetic lethal inference as potential anti-cancer target gene detection
Drug-target name | Drug (Description) |
---|---|
CDC25B | Beta-Mercaptoethanol (Glutathione S-Transferase inhibitor); Cysteinesulfonic Acid(Peroxiredoxin inhibitor); Double Oxidized Cysteine (Peptide Deformylase Pdf1 inhibitor) |
CDC42 | Aminophosphonic Acid-Guanylate Ester (G25K GTP-Binding Protein inhibitor) |
CDK2 | 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine (Cell Division Protein Kinase 2 inhibitor) |
DDX6 | D-tartaric acid (D-tartaric acid) |
EIF4E | 7-Methyl-Gpppa (Eukaryotic Translation Initiation Factor 4E inhibitor); 7n- Methyl-8-Hydroguanosine-5'-Diphosphate (Vp39 inhibitor) |
GDI1 | Geran-8-Yl Geran(Rab GDP Disossociation Inhibitor Alpha inhibitor) |
GRB2 | 4- [(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo- 7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid (Growth Factor Receptor-Bound Protein 2 inhibitor) |
HSP90AB1 | 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine (Heat Shock Protein Hsp 90-Beta inhibitor) |
HSPA5 | antihemophilic factor (Coagulation factor VIII precursor) |
LSS | Dihydrofolic Acid (Dihydrofolate Reductase inhibitor) |
PPP1CC | 9,10-Deepithio-9,10-Didehydroacanthifolicin (Serine/Threonine Protein Phos phatase Pp1-Gam inhibitor) |
PPP2CA | Vitamin E (Dietary supplement) |
PPP3R2 | Cyclosporine (Investigational Immunomodulatory Agents; Immunosuppressive Agents; Antifungal Agents; Dermatologic Agents; Enzyme Inhibitors; An tirheumatic Agents For treatment of transplant rejection, rheumatoid arthritis, severe psoriasis) |
PRDX2 | 3-Sulfinoalanine (3-Hydroxy-3-Methylglutaryl-Coa Synthase inhibitor) |
SEC14L2 | Palmitic Acid (Enzyme Inhibitors) |
SNAP25 | Botulinum Toxin Type A (Anti-Wrinkle Agents; Antidystonic Agents; Neuromuscular Blocking Agents) |
SOD1 | S-Oxy Cysteine (Prolyl Oligopeptidase inhibitor) |
SQLE | Naftifine (Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents) |