Figure 2
From: Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics
Molecular profiles of molecular components at different EGF concentrations. 50 ng/ml(green line), 25 ng/ml (blue line), and 0.5 ng/ml (red line). The (EGF-EGFR*)2 indicates the dimerized and autophosphorylated form of the EGF receptor. Shc* and Raf* is the phosphorylated form of cellular Shc and Raf. Ras-GTP is the formed complex of Ras and GTP. MEK-PP and ERK-PP are the doubly phosphorylated forms of MEK and ERK.