Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3

BMC Systems Biology

Table 1 Physiological characterization of the reference and sdh3 Δ strains in aerobic and anaerobic batch cultivations

Strain	Condition	μ _max	Y_sx	Y_ssuc	Y_se	Y_sac	Y_sg	Y_spyr
sdh3 Δ	Aerobic	0.25 ± 0.03	0.083 ± 0.003	0.0027 ± 0.0001	0.35 ± 0.002	0.0062 ± 5.7·10^-5	0.108 ± 0.004	0.0061 ± 0.0003
sdh3 Δ	Anaerobic	0.27	0.086	0.0033	0.36	0.0065	0.097	0.0041
WT	Aerobic	0.31 ± 0.04	0.10 ± 0.01	TA	0.34 ± 0.01	0.0042 ± 0.0008	0.073 ± 0.010	TA
WT	Anaerobic	0.34	0.10	0	0.35	0.0050	0.106	0.0027

The yield coefficients for biomass, ethanol, glycerol, pyruvate and acetate were determined in the exponential growth phase from linear regression of their concentration as a function of the residual glucose concentration. Succinate yield was calculated at a fermentation end-point. Y_sx: grams of biomass per g of glucose consumed. Y_ssuc: grams of succinate per g of glucose consumed. Y_se: grams of ethanol per g of glucose consumed. Y_sac: grams of acetate per g of glucose consumed. Y_sg: grams of glycerol per g of glucose consumed. Y_spyr: grams of pyruvate per g of glucose consumed. μ_max : maximum specific growth rate in h^-1. TA: trace amount.

ISSN: 1752-0509